Synthesis, structural characterization and antibacterial activity of diorganotin N-(salicylidene)tyrosinates
Received: November 08, 2019; accepted: December 16, 2019
Abstract
O-3-X-5-YC6H2CH=NCH(CH2C6H4OH-4)COO] (R, X, Y = Et, H, H (1); n-Bu, H, Br (2); n-Bu, Br, Br (3)), have been synthesized by the one-pot reaction of diorganotin oxide, (L)-tyrosine and salicylaldehyde, and characterized by elemental analysis, IR, NMR, and X-ray single crystal diffraction. X-Ray analyses of 1-3 show that the tin atoms of the complexes exhibit distorted trigonal-bipyramidal geometries. The intermolecular O-H⋅⋅⋅O hydrogen bonds connect the molecules into one-dimensional supramolecular chain or a R22(20) macrocyclic dimer. Bioassay results show that 1-3 have good in vitro antibacterial activity against Escherichia coli.
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Published
2019-11-19
How to Cite
Tian, L., Chen, L., & Wang, L. (2019). Synthesis, structural characterization and antibacterial activity of diorganotin N-(salicylidene)tyrosinates. Communications in Inorganic Synthesis, 7(1), 7-12. Retrieved from https://revistas.usach.cl/ojs/index.php/Inorganic/article/view/4304
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